Lumbar disk herniation, susceptibility to

This study tests whether a special device placed during disc surgery can help people return to normal activities faster by preventing the disc from herniating again. About 120 adults with a herniated disc in the lower back will be randomly assigned to different post-surgery activ…

This trial tests whether a hands-on spinal manipulation technique, called lever positioning manipulation, can ease the leg and back pain caused by a herniated disc. About 84 adults with a herniated disc will receive either the real manipulation or a sham version three times a wee…

This study tests whether giving magnesium during back surgery can reduce the confusion and agitation some patients feel when waking up. 70 adults having a single-level lumbar microdiscectomy will receive either magnesium or a placebo. Researchers will monitor agitation, pain, and…

This study looks at two ways to help people recover after surgery for a slipped disc in the lower back. One group will start moving early, and the other will do the same plus get mild electrical stimulation on their muscles. The goal is to see which approach reduces pain and impr…

This study tests whether electroacupuncture can improve sleep in people with long-term sciatica caused by a slipped disc. About 114 adults with chronic insomnia and leg pain will receive either real electroacupuncture or a sham version three times a week for four weeks. Researche…

This study looks at whether adding high-intensity laser therapy to exercise can reduce pain and improve daily function for people with a slipped disc in the lower back. About 150 adults aged 18 to 65 will be split into three groups: exercise alone, exercise plus laser, or exercis…

This study looks at whether doing physical therapy in the daytime or evening helps people with a herniated disc in their lower back sleep better and feel less sleepy during the day. It includes 60 adults who also have a high risk for obstructive sleep apnea. Participants will be …

This study tests whether using virtual reality to educate patients before lumbar disc surgery reduces their anxiety more than standard education. About 56 adults scheduled for back surgery will be randomly assigned to either a VR education session or routine education. Researcher…

This study looks at people with a single herniated disc in the lower back who are getting laser disc surgery. Some will also receive a steroid injection during the same procedure. Researchers will track pain, daily function, and need for more treatments to see if the extra inject…

This study compares two surgical techniques for fusing bones in the lower back: using two straight cages or one curved (banana-shaped) cage. The goal is to see which method provides better pain relief, faster recovery, and fewer complications. About 30 adults with chronic back pa…

This study will test two different levels of positive pressure (PEEP) on a breathing machine during lumbar spine surgery performed face-down. The goal is to see which setting helps patients breathe better and maintain good oxygen levels. Sixty adults aged 18-65 having elective ba…

This study reviews medical records of 120 adults with low back pain who completed 15 sessions of physical therapy. Researchers will group patients based on their MRI results (disc herniation, disc degeneration, or normal findings) to see if certain types of back pain respond bett…

This study looks at 96 adults with lower back pain to see if the damage shown on an MRI matches how much pain they actually feel. Participants will fill out pain and disability questionnaires and get a physical exam. The goal is to help doctors better understand and treat back pa…

This study will follow 120 adults with sciatica from a herniated disc who receive a standard steroid injection. Researchers want to see if the speed and pattern of pain relief in the first few days and weeks can predict whether the treatment is still working at 3 and 6 months. Pa…

This study will observe how different spinal problems—like scoliosis, stenosis, or herniated discs—change the way people walk and use their back muscles. Researchers will compare 120 older adults (age 60+) with these conditions to healthy volunteers using motion cameras and muscl…

This study compares two minimally invasive surgical techniques—uniportal and biportal endoscopy—for treating a single-level lumbar disc herniation. Sixty adults aged 18-70 with persistent symptoms will be randomly assigned to one of the two procedures. The main goal is to see whi…