Hemorrhagic stroke

This study is testing a device called a flow modulator to treat wide-necked brain aneurysms. The device is placed inside the artery to redirect blood flow away from the aneurysm, helping it close off. Researchers will check if the device is safe and effective in 214 adults over 1…

This study tests whether clot-busting drugs (alteplase or tenecteplase) are safe and effective for stroke patients who have taken a blood thinner (FXa inhibitor) in the last 48 hours. Current guidelines avoid this treatment due to bleeding concerns, but new evidence suggests it m…

This study tests whether giving stroke patients a personalized diet plan within two days can lower the risk of death within 30 days. About 3,084 adults with moderate to severe stroke will take part. Dietitians will track food intake and adjust nutrition, using supplements or tube…

This study tests whether functional electrical stimulation (FES) can help people who have had a stroke or traumatic brain injury regain handwriting skills. Participants are randomly assigned to receive FES during handwriting practice or standard therapy. Using motion capture tech…

This study tests whether starting a special exercise program soon after a stroke can protect the brain from memory loss and dementia. Researchers will enroll 120 people who had a stroke in the past 6 months. Participants will do a mix of exercises, and the study will measure chan…

This study compares a new 'virtual stroke unit' approach to standard stroke unit care for people with a stroke who are not eligible for a clot removal procedure. The virtual unit uses video calls and monitoring equipment to let a specialist team at a main hospital help guide care…

This study tests a nurse-led program called BEST CARE ICTUS_HC for adults hospitalized with acute stroke in hospitals without specialized stroke units. The program includes staff training, swallowing tests, and environmental adaptations to help with attention and safety. Research…

This study tests whether amantadine, a drug already used for flu and Parkinson's, can help people recover after a stroke. Sixty adults who had an ischemic or hemorrhagic stroke will receive either amantadine or a placebo for one month. Researchers will track side effects and meas…

This study tests whether adding the antibiotic minocycline to standard stroke care can improve survival and reduce disability in adults who have had a moderate stroke. About 1,164 participants will be randomly assigned to receive either minocycline pills for five days plus usual …

This study tests whether taking atorvastatin (a cholesterol-lowering drug) before and after a brain stent procedure can prevent strokes and other serious events. About 354 adults with brain aneurysms will be randomly assigned to receive either atorvastatin or a placebo. The goal …

This study tests a surgery that moves a nerve from the neck to help people with arm weakness after a stroke. It is for those whose arm has not improved with rehab. The goal is to see if the surgery can improve arm movement and control.

This study tests two programs for people recovering from a stroke who are leaving inpatient rehab to go home. Half of the 520 participants will get a standard stroke education program, while the other half will get a program that helps modify their home environment. The goal is t…

This study tests a new microcatheter device (Aristotle 14 guidewire and Plato 17 microcatheter) for treating chronic subdural hematoma, a type of brain bleed. About 100 adults will be randomly assigned to receive the new device or the surgeon's usual choice. Researchers will comp…

This study compares two ways to help stroke survivors control their blood pressure: home monitoring alone versus home monitoring plus group medical visits. High blood pressure is the leading cause of a second stroke, so the goal is to find a better method to keep blood pressure i…

This trial tests a new portable brain scanner designed to quickly detect bleeding in the brain (hemorrhagic stroke) using harmless radio waves. The helmet-like device could offer a faster, more accessible alternative to CT or MRI scans in emergency settings. Researchers will enro…

This study evaluates a portable, low-field MRI device (Hyperfine Swoop) for diagnosing stroke in people arriving at the emergency department with symptoms lasting less than 12 hours. Participants receive the low-field scan in addition to standard CT imaging. The goal is to see if…

This study is looking for markers in blood and saliva that can quickly tell if a person is having a stroke, and what kind. Researchers will collect samples from 650 adults with suspected stroke within 24 hours of symptoms. The goal is to develop a fast, accurate test to help emer…

This study is testing whether machine learning and special brain injury markers in blood and spinal fluid can warn doctors early when a patient with a brain bleed is developing delayed cerebral ischemia (lack of oxygen to the brain). Researchers will monitor 1,500 adults in inten…

This trial tests whether a non-invasive electrical stimulation applied to specific acupoints on the fingers can improve memory, attention, and decision-making in people who have had a stroke. Adults aged 35 to 80 with mild to moderate cognitive impairment after an ischemic stroke…

This study looks at whether a regular exercise program can improve the benefits of botulinum toxin (Botox) injections for arm stiffness after a stroke. About 70 stroke survivors with arm spasticity will receive Botox and then be randomly assigned to either a prescribed exercise r…

This study looks at urinary problems in people recovering from a stroke. Researchers compare patients with and without bladder issues and test two simple behavioral approaches: for those with thinking difficulties, training to go to the toilet immediately when they feel the urge;…

This small pilot study tests whether a drug called cerebrolysin can help people who have been unconscious for over a month after a hemorrhagic stroke. Twelve adults aged 19 to 80 will receive either the drug or a placebo daily for two weeks. Researchers will measure changes in co…

This study tests a new rehabilitation method for people who lost part of their vision after a stroke. It combines gentle electrical brain stimulation with visual exercises, sometimes using virtual reality, to try to speed up recovery of sight in the blind area. The study involves…

This study tests whether using EEG neurofeedback — a way to train brain activity — can improve arm movement in people who recently had a stroke. Forty adults with a stroke within the past three weeks will either get real or fake (sham) neurofeedback, plus standard rehab. The goal…

This study tests whether a personalized form of brain stimulation (tDCS) can help people who had a stroke more than 3 months ago regain arm movement. Researchers will use brain scans to tailor the stimulation to each person and measure changes in brain connectivity and motor func…

This study tests whether a non-invasive nerve stimulation (taVNS) combined with occupational therapy can improve arm movement in people who had a stroke at least 6 months ago. 60 participants will receive the stimulation during therapy sessions. The goal is to see if this approac…

This study tests whether a gentle electrical current applied to the brain, combined with walking and thinking exercises, can improve movement and thinking in people who have had a stroke. Sixty adults who had a stroke between 2 weeks and 5 years ago will participate. The goal is …

This small pilot study tests whether a brain-computer interface combined with electrical stimulation can improve swallowing difficulties and language problems in people who had a stroke at least three months ago. Ten participants will use the device for hand rehabilitation while …

This study compares robot-assisted training to standard physical therapy for people who have had a stroke and still have moderate-to-severe movement problems. Forty participants who are 6-24 months post-stroke will be randomly assigned to one of two training programs. The goal is…

This study follows 65 infants who had a stroke around birth, tracking their brain development and motor skills over two years. Researchers use MRI scans, brain stimulation, and movement tests to find markers of recovery. The goal is to understand how the brain heals, which could …

This study examines how hospital admissions and treatments for stroke and transient ischemic attack (TIA) changed during the COVID-19 pandemic across Europe. Researchers will collect data from about 40 stroke units, covering admissions, length of stay, and procedures like thrombo…

This study tests different power levels and timing of low-intensity focused ultrasound (LIFUS) to see which best improves arm movement and motor learning in stroke survivors. 24 adults who had a stroke at least 6 months ago and have arm weakness will participate. The goal is to f…

This study is for adults 18 and older who have had a stroke or a transient ischemic attack (TIA), often called a mini-stroke. The goal is to collect information from standard medical tests and some extra research tests, like blood draws and brain scans, to better understand how t…

This study tests whether a one-on-one nursing education session just before a stroke patient goes home can improve how well they follow their medication and care plan. Researchers will enroll 300 stroke survivors who are returning home and randomly assign half to receive the extr…

This study tests whether a wireless sensor placed on the forehead can accurately measure oxygen levels in the brains of infants in the neonatal intensive care unit (NICU). The wireless device is compared side-by-side with the standard wired monitor in 20 newborns with conditions …

This study tests whether a 6-week program that combines a pedometer with phone or video coaching is practical for people who had a stroke at least 6 months ago. 24 participants will track their steps and set goals with an occupational therapist. The main goal is to see if people …

This early-stage study tests a technique that uses electrical stimulation to help stroke survivors improve arm movement. The idea is to correct mismatched sensory signals between vision and body awareness, which can interfere with motor learning. Only 3 people with chronic stroke…

This study follows 2000 adults who are in a coma or have disorders of consciousness after serious brain injuries like stroke, cardiac arrest, or trauma. Researchers collect medical records and later interview survivors or their caregivers about physical and emotional recovery. No…

This study tests whether adding immersive virtual reality (VR) to standard physical therapy helps people who recently had a stroke regain arm movement and improve quality of life. Researchers will also look at blood markers and genes that might predict recovery. About 120 adults …

This study tests a new set of procedures called the HI-SPEED Protocol, designed to help hospitals evaluate stroke patients faster and decide who needs to be transferred for advanced care. The goal is to reduce the time patients spend in the first hospital before being moved to a …

This study aims to create an artificial intelligence (AI) model to help doctors diagnose and predict recovery for people with a bleeding stroke (spontaneous intracerebral hemorrhage). The researchers will use brain scans and other data from 7,100 patients to train the AI. The goa…

This study tests a new brain scanning method called fNIRS to see if it can predict recovery in unconscious ICU patients with severe stroke or brain injury. Researchers will compare fNIRS results with standard tests in 30 patients and healthy volunteers. If successful, fNIRS could…

This study looks at whether an imbalance in gut bacteria is linked to stroke risk and recovery in young adults (ages 18-45). Researchers will analyze stool and blood samples from 60 stroke patients to find patterns that could help predict strokes earlier. The goal is to understan…

This study looks at whether low magnesium in the blood is linked to memory, attention, and other thinking problems after a stroke. Researchers will measure magnesium levels and give cognitive tests to 80 stroke patients over several weeks. The goal is to understand if magnesium d…

This study looks at 1000 adults with brain hemorrhage to see if the shape of the blood clot (hematoma) early on can predict whether the bleeding will get worse. Researchers will also compare different treatments to find the best approach. The goal is to improve recovery and reduc…

This study aims to see if blood markers for Alzheimer's and brain injury can help predict death and hospital readmission in older patients. Researchers will follow 400 hospitalized seniors, including those with neurological issues or dementia. The goal is to develop a tool that u…

This study looks at whether caregivers' expectations for stroke patients' recovery match what physical therapists think is achievable. Researchers will compare goals set by caregivers and therapists for 58 subacute stroke patients. The aim is to improve how rehabilitation goals a…

This study compares bone density in 84 stroke patients at different recovery stages (1 week to 6 months, or over 1 year) to understand osteoporosis risk. Researchers will also look at factors like muscle strength and vitamin D levels. The goal is to identify high-risk patients wh…

This study is testing a new type of MRI scanner, called Field-Cycling Imaging (FCI), to see if it can detect brain changes within the first day of a stroke. Researchers will compare FCI scans with standard MRI scans in 40 acute stroke patients. Participants will also provide bloo…

This study looks at whether a heart ultrasound technique called left atrial strain can predict stroke risk in people who had a stroke with no known cause. Researchers will measure heart function in 900 adults and track who has another stroke. The goal is to find a safe, low-cost …

This study is building a large registry of people who have had a stroke and still have symptoms. The goal is to connect them with researchers studying new ways to improve recovery. No treatments or tests are given—just observation and data collection.

This study will use routine EEG recordings in 100 stroke patients to see if brain activity patterns can predict who will develop epilepsy. Researchers also aim to detect hidden (subclinical) seizures that may affect recovery. The study is observational, meaning no new treatment i…