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Brain zaps + treadmill: new combo therapy aims to rewire Stroke-Damaged brains

NCT ID NCT07236216

Symptom relief Sponsor: Mahidol University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a gentle electrical current applied to the brain, combined with walking and thinking exercises, can improve movement and thinking in people who have had a stroke. Sixty adults who had a stroke between 2 weeks and 5 years ago will participate. The goal is to see if this combination therapy helps the brain and nerves work better.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2025

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Unilateral stroke individuals aged 18-80 years. 2. A first-ever stroke. 3. Stroke onset from at least 2 weeks-5 years. 4. Able to walk independently with or without gait aids (modified Rankin scale (mRS) 1-3) 5. Montreal cognitive Assessment-Thai version (MoCA-T) greater than or equal to 20 scores. 6. Ability to read, communicate, follow and understand instructions. Exclusion Criteria: 1. Presence of any psychological or neurological antecedent, unstable medical conditions or condition that may increase risk of stimulation such as epilepsy, seizure, and history of brain injury 2. Having unstable cardiovascular disease or respiratory disease, and uncontrolled chronic disease such as diabetes mellitus (DM), hypertension (HT) and chronic kidney disease (CKD) 3. Receiving other non-invasive brain stimulation or additional intervention such as TMS, PMS or acupuncture 4. Presence of metal implantation, intracranial shunt, cochlear implantation, or cardiac pacemakers. 5. Presence of an opened wound, infectious wound around scalp or craniectomy with unreplaced bone flap 6. Moderate pain (numeric pain rating score \> 4/10) in any joint of the upper or lower limb, whether paretic or non-paretic 7. Presence of color blindness 8. Presence of any substance use including cannabis and kratom

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Conditions

The condition(s) this trial relates to.

hemorrhagic stroke ischemic stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic stroke patient Hemorrhagic stroke Ischemic stroke Subacute stroke

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Faculty of Physical Therapy, Mahidol University

    RECRUITING

    Nakhon Pathom, 73170, Thailand

More trials for these conditions

Other studies related to the condition(s) this trial covers.