Gingival recession

This trial tests whether adding injectable platelet-rich fibrin (i-PRF) or hyaluronic acid gel to standard free gingival graft surgery improves healing and reduces graft shrinkage. Adults with gum recession and insufficient keratinized tissue will be randomly assigned to one of t…

This trial tests whether a modified gum graft technique, called a vertically coronally advanced flap, covers exposed tooth roots better than the standard coronally advanced flap. Both methods use a connective tissue graft to thicken the gum. Researchers will measure how much the …

This study compares two materials used in gum graft surgery for people with thin or missing gum tissue around teeth or dental implants. One group receives a graft made from their own palate tissue, while the other group receives a graft made from a collagen matrix derived from pi…

This study tests whether a special collagen matrix can replace tissue taken from the roof of the mouth to fix receding gums. Forty adults with at least two areas of gum recession will receive either the collagen matrix or a standard palate graft. The main goal is to see how much …

This trial tests whether adding a gel made of hyaluronic acid and polynucleotides to standard gum graft surgery helps cover receding gums better. Twelve people with receding gums will receive the surgery with the gel applied to the graft. Over six months, the study measures how m…

This study looks at how well 3D printed bone grafts work for supporting dental implants in people with gum disease or bone loss. Researchers will check if the implants stay stable and how much the graft shrinks over 1 to 6 years. About 100 healthy adults who already received this…

This study tests whether a cream made from phenytoin, a seizure drug known to cause gum overgrowth, can help receding gums grow back. Thirty adults who want to avoid surgery will apply either the phenytoin cream or a placebo paste. Researchers will measure changes in gum attachme…

This pilot study tests whether a gel made from a special form of hyaluronan (HA35) can help people with mild gum recession and chronic gum inflammation. Thirty adults will apply the gel to their gums and teeth twice a day for 42 days. Researchers will measure changes in gum reces…

Gum recession exposes tooth roots, causing sensitivity and cosmetic concerns. Standard surgery (CAF + SCTG) covers the root, but healing can be slow. This trial tests whether adding a hyaluronic acid gel (hyaDENT BG®) to the surgery improves root coverage and recovery. Thirty-fou…

This study tests whether adding cross-linked hyaluronic acid through microneedling after gum surgery can improve gum thickness and cover exposed tooth roots better than microneedling alone. It involves 22 adults with a single gum recession and thin gums. Participants will receive…

This study tests a new program that teaches pregnant women in Bangladesh how to care for their teeth and gums during routine prenatal visits. Over 95% of pregnant women in Bangladesh have gum disease, but oral health is not part of standard pregnancy care. The study will compare …

This study compares two surgical techniques to treat single gum recession defects, where the gum has pulled away from the tooth. One method uses a tunnel without cuts, the other adds a small cut. The goal is to see which covers the exposed root better and is less invasive. The tr…

This study tests whether breath samples collected in special bags remain stable for up to 7 days, which could allow people with bad breath (halitosis) to provide samples from home instead of traveling to a clinic. Researchers will compare gas levels measured right away and after …

This study will check if a simple questionnaire can accurately identify gum disease in adults. About 291 participants in Saudi Arabia will fill out the questionnaire and then have a standard dental exam. The goal is to see how well the questionnaire matches the exam results, whic…

This study will enroll 2,000 adults to see if non-invasive methods like smartphone photos, dental X-rays, and questionnaires can accurately detect gum disease compared to a standard clinical exam. Researchers will use artificial intelligence to analyze the images and combine data…

Researchers at the University of Iowa are studying people with thin gum tissue who need a gum graft to cover exposed tooth roots. The trial compares two ways of preparing the gum bed before placing a graft: removing all tissue down to the bone, or leaving a thin layer of tissue o…

This trial tests whether low-level laser therapy or a hyaluronic acid gel can improve healing after free gingival graft surgery, a procedure to treat receding gums. Adults with insufficient gum tissue in the lower front teeth will receive surgery alone, surgery plus laser, or sur…

This study looks at whether smoking changes the tissue in the roof of the mouth where a gum graft is taken, and whether that affects how well the graft covers exposed tooth roots. It will compare 12 smokers with 12 non-smokers, all receiving the same surgical procedure for gum re…

This study looks at how the mouth heals after gum surgery in people with and without diabetes. Researchers will measure wound size and track healing over 12 weeks. They will also check bacteria and inflammation levels to see what affects recovery. The goal is to learn why healing…

This study looks at how well the mouth heals after gum surgery in people with diabetes compared to those without. Researchers will track healing, measure gum recession, and check factors like bacteria and inflammation. The goal is to understand what affects recovery in diabetic p…

This study looks at whether a gel made from polynucleotides and hyaluronic acid can help gum tissue heal better after a graft is taken from the roof of the mouth. Fifteen adults with gum recession will have grafts taken from both sides of their palate in two separate surgeries, n…

This study looks at how much final-year dentistry and psychology students know about gum disease (periodontitis) and whether that knowledge is linked to their own gum health. About 60 students will fill out a questionnaire and get a dental check-up. The goal is to see if more kno…