Can a gel boost gum grafts to cover exposed tooth roots?
NCT ID NCT07771244
First seen Aug 18, 2026 · Last updated Aug 21, 2026 · Updated 2 times
Summary
This trial tests whether adding a gel made of hyaluronic acid and polynucleotides to standard gum graft surgery helps cover receding gums better. Twelve people with receding gums will receive the surgery with the gel applied to the graft. Over six months, the study measures how much root is covered, gum thickness, pain, and patient satisfaction.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- hyaluronic acid and polynucleotides injected into the gum graft during surgery
- What this could lead to
- If it works, this could make gum graft surgery more effective at covering exposed tooth roots and reduce post-operative pain.
- What could go wrong
- This is a small early-stage study with only 12 patients, so results may not apply to everyone. The added substances could cause irritation or fail to improve outcomes beyond standard surgery.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 12 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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15 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with RT II gingival recession. * Age range: 15-60 years. * Systemically healthy patients with no contraindications to surgery. * Patients who have not had previous periodontal surgery in the area of treatment. Exclusion Criteria: * Periodontitis. * Active systemic disease affecting wound healing. * Pregnancy or breastfeeding. * Improperly aligned teeth or teeth with cervical restorations or crowns. * Non-carious cervical lesions
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Faculty of Dentistry, Cairo University
Cairo, Egypt