Cranial nerve neuropathy
MONDO:0003569A neoplastic or non-neoplastic disorder that affects one of the cranial nerves.
Also known as: cranial nerve disease, cranial nerve disorder, cranial neuron projection bundle disease, cranial neuron projection bundle disease or disorder, cranial neuropathy, disease of cranial neuron projection bundle, disease or disorder of cranial neuron projection bundle, disorder of cranial nerve
392 clinical trials for this condition and its sub-types, 4 tagged with Cranial nerve neuropathy itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Cranial nerve neuropathy
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Cranial nerve palsy 2 trials · 122 incl. sub-types
7 sub-types
- Oculomotor nerve paralysis 1 trial · 87 incl. sub-types Sub-types →
- Bell's palsy 29 trials Sub-types →
- Progressive bulbar palsy 5 trials Sub-types →
- Abducens nerve palsy 2 trials
- Fourth cranial nerve palsy 1 trial Sub-types →
- Glossopharyngeal nerve paralysis 0 trials
- Multiple cranial nerve palsy 0 trials Sub-types →
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Optic nerve disorder 23 trials · 96 incl. sub-types
8 sub-types
- Optic atrophy 4 trials · 26 incl. sub-types Sub-types →
- Optic neuritis 21 trials · 25 incl. sub-types Sub-types →
- Low tension glaucoma 21 trials
- Anterior ischemic optic neuropathy 9 trials · 11 incl. sub-types Sub-types →
- Optic nerve neoplasm 1 trial · 4 incl. sub-types Sub-types →
- Optic disk drusen 1 trial
- Extensive peripapillary myelinated nerve fibers 0 trials
- Isolated optic nerve aplasia 0 trials
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Third cranial nerve disorder 1 trial · 87 incl. sub-types
2 sub-types
- Oculomotor nerve paralysis 1 trial · 87 incl. sub-types Sub-types →
- Oculomotor nerve neoplasm 0 trials Sub-types →
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Ocular motility disease 4 trials · 65 incl. sub-types
6 sub-types
- Strabismus 28 trials · 46 incl. sub-types Sub-types →
- Ophthalmoplegia 0 trials · 11 incl. sub-types Sub-types →
- Pathologic nystagmus 7 trials · 9 incl. sub-types Sub-types →
- Tolosa-Hunt syndrome 1 trial
- Congenital fibrosis of extraocular muscles 1 trial Sub-types →
- Weber syndrome 0 trials
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Trigeminal nerve disorder 3 trials · 63 incl. sub-types
4 sub-types
- Trigeminal neuralgia 37 trials
- Trigeminal autonomic cephalalgia 8 trials · 27 incl. sub-types Sub-types →
- Ophthalmic herpes zoster 0 trials
- Trigeminal nerve neoplasm 0 trials Sub-types →
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Facial nerve disorder 4 trials · 53 incl. sub-types
9 sub-types
- Bell's palsy 29 trials Sub-types →
- Facial neuralgia 16 trials
- Clonic hemifacial spasm 4 trials
- Facial hemiatrophy 3 trials
- Mobius syndrome 2 trials Sub-types →
- Melkersson-Rosenthal syndrome 0 trials
- Facial nerve neoplasm 0 trials
- Geniculate ganglionitis 0 trials
- Isolated facial myokymia 0 trials
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Cranial neuralgia 0 trials · 53 incl. sub-types
4 sub-types
- Trigeminal neuralgia 37 trials
- Facial neuralgia 16 trials
- Glossopharyngeal neuralgia 2 trials
- Combined hyperactive dysfunction syndrome of the cranial nerves 0 trials
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Olfactory nerve disorder 8 trials · 12 incl. sub-types
1 sub-type
- Olfactory nerve neoplasm 0 trials · 4 incl. sub-types Sub-types →
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Vestibulocochlear nerve disorder 2 trials · 11 incl. sub-types
2 sub-types
- Vestibular neuronitis 9 trials
- Vestibulocochlear nerve neoplasm 0 trials Sub-types →
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Glossopharyngeal nerve disorder 2 trials · 8 incl. sub-types
5 sub-types
- Vagus nerve disorder 4 trials Sub-types →
- Glossopharyngeal neuralgia 2 trials
- Glossopharyngeal motor neuropathy 0 trials
- Glossopharyngeal nerve neoplasm 0 trials Sub-types →
- Glossopharyngeal nerve paralysis 0 trials
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Cranial nerve neoplasm 0 trials · 8 incl. sub-types
12 sub-types
- Malignant cranial nerve neoplasm 0 trials · 4 incl. sub-types Sub-types →
- Olfactory nerve neoplasm 0 trials · 4 incl. sub-types Sub-types →
- Optic nerve neoplasm 1 trial · 4 incl. sub-types Sub-types →
- Abducens nerve neoplasm 0 trials
- Facial nerve neoplasm 0 trials
- Glossopharyngeal nerve neoplasm 0 trials Sub-types →
- Hypoglossal nerve neoplasm 0 trials Sub-types →
- Oculomotor nerve neoplasm 0 trials Sub-types →
- Spinal accessory nerve neoplasm 0 trials
- Trigeminal nerve neoplasm 0 trials Sub-types →
- Trochlear nerve neoplasm 0 trials
- Vestibulocochlear nerve neoplasm 0 trials Sub-types →
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Jaw-winking syndrome 2 trials
2 sub-types
- Marin-Amat syndrome 0 trials
- Inverse Marcus-Gunn phenomenon 0 trials
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Abducens nerve disorder 0 trials · 2 incl. sub-types
2 sub-types
- Abducens nerve palsy 2 trials
- Abducens nerve neoplasm 0 trials
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Accessory nerve disorder 1 trial
1 sub-type
- Spinal accessory nerve neoplasm 0 trials
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Hypoglossal nerve disorder 1 trial
1 sub-type
- Hypoglossal nerve neoplasm 0 trials Sub-types →
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Trochlear nerve disorder 1 trial
2 sub-types
- Fourth cranial nerve palsy 1 trial Sub-types →
- Trochlear nerve neoplasm 0 trials
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Pseudobulbar palsy 0 trials
Most studied deeper sub-types
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Herbal supplement fails to show clear benefit in optic neuritis pilot
Disease control Stopped earlyThis small pilot study tested whether adding gypenosides (a herbal supplement) to standard steroid treatment could help protect the nerve at the back of the eye in adults having their first episode of acute optic neuritis. Ten participants were enrolled, but the study was stopped…
Phase 2 • Sponsor: First Affiliated Hospital of Guangxi Medical University • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Old allergy drug may help repair nerves in MS patients
Disease control Stopped earlyThis study tested whether clemastine fumarate, an allergy medication, could improve eye movement problems in people with multiple sclerosis (MS). The trial planned to enroll 80 MS patients with a specific eye condition called internuclear ophthalmoparesis, but was terminated earl…
Phase 3 • Sponsor: Amsterdam UMC, location VUmc • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Experimental drug aims to curb disinhibition in dementia patients
Symptom relief Stopped earlyThis study tested a drug called AVP-786 to see if it could safely reduce disinhibition—impulsive or inappropriate behavior—in people with neurodegenerative disorders like Alzheimer's or frontotemporal dementia. The trial planned to include many participants but was terminated ear…
Phase 2 • Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 12:32 UTC
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Nerve pain device study abandoned after only 2 patients
Symptom relief Stopped earlyThis study tested a device called Exablate, which uses focused sound waves to treat areas of the brain linked to pain. The goal was to see if it could reduce pain and improve quality of life in people with chronic nerve pain. Only 2 people enrolled before the study was stopped, s…
Sponsor: InSightec • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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New device uses humming vibrations to zap sinus pain
Symptom relief Stopped earlyThis study tested a device called SinuSonic that uses sound vibrations and pressure to relieve sinus headache pain. The trial included 27 adults with facial pain lasting more than 3 months. Participants used either the real device or a sham device that looked the same but didn't …
Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 26, 2026 15:53 UTC
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New brain wave test could predict vertigo recovery
Knowledge-focused Stopped earlyThis study tested a new method called cortical vestibular evoked potentials (C-VEPs) to measure how the brain processes balance signals from the inner ear. Researchers compared people with normal balance to those with vestibular neuronitis (a cause of vertigo) to see if the test …
Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Nurse phone calls may boost headache treatment success
Knowledge-focused Stopped earlyThis study looked at whether follow-up calls from a headache nurse could help patients with migraines, tension headaches, cluster headaches, or hemicrania continua stay on their preventive medication. 147 participants were randomly assigned to receive nurse calls at 2 and 6 weeks…
Sponsor: Norwegian University of Science and Technology • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC