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Promising disinhibition drug trial halted after just one participant

NCT ID NCT02534038

First seen May 14, 2026 · Last updated May 24, 2026 · Updated 4 times

Summary

This study tested an experimental drug called AVP-786 to see if it could safely reduce disinhibition—acting impulsively or inappropriately—in people with brain disorders like Alzheimer's or dementia. Only one person enrolled before the trial was stopped early. The main goal was to measure changes in behavior using a standard caregiver questionnaire.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Cleveland Clinic Lou Ruvo Center for Brain Health

    Las Vegas, Nevada, 89106, United States

Conditions

Explore the condition pages connected to this study.