Promising disinhibition drug trial halted after just one patient

NCT ID NCT02534038

First seen May 14, 2026 · Last updated May 16, 2026 · Updated 1 time

Summary

This study tested a drug called AVP-786 to see if it could help control disinhibition—acting without thinking—in people with brain diseases like Alzheimer's or frontotemporal dementia. The trial was stopped early after enrolling only one participant, so no conclusions can be drawn about the drug's safety or effectiveness.

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Contacts and locations

Locations

  • Cleveland Clinic Lou Ruvo Center for Brain Health

    Las Vegas, Nevada, 89106, United States

Conditions

Explore the condition pages connected to this study.