Childhood neoplasm
MONDO:0021079A benign or malignant neoplasm arising during childhood.
Also known as: childhood neoplasm, childhood neoplasm (disease), childhood tumor, childhood tumour, neoplasm (disease) of childhood, paediatric neoplasm, paediatric neoplasm (disease), paediatric tumour
2059 clinical trials for this condition and its sub-types, 46 tagged with Childhood neoplasm itself.
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Sub-types of Childhood neoplasm
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Childhood malignant neoplasm 241 trials · 600 incl. sub-types
30 sub-types
- Childhood leukemia 23 trials · 172 incl. sub-types Sub-types →
- Pediatric lymphoma 3 trials · 141 incl. sub-types Sub-types →
- Childhood brain stem neoplasm 3 trials · 95 incl. sub-types Sub-types →
- Pediatric hepatocellular carcinoma 36 trials
- Childhood malignant kidney neoplasm 0 trials · 30 incl. sub-types Sub-types →
- Pediatric high-grade glioma 14 trials · 16 incl. sub-types Sub-types →
- Childhood precursor T-lymphoblastic lymphoma/leukemia 0 trials · 13 incl. sub-types Sub-types →
- Pediatric osteosarcoma 8 trials Sub-types →
- Childhood central nervous system primitive neuroectodermal neoplasm 6 trials Sub-types →
- Pleuropulmonary blastoma 4 trials Sub-types →
- Malignant childhood germ cell neoplasm 0 trials · 3 incl. sub-types Sub-types →
- Pediatric fibrosarcoma 0 trials · 2 incl. sub-types Sub-types →
- Pediatric intraocular retinoblastoma 2 trials
- Childhood choroid plexus carcinoma 1 trial
- Childhood malignant schwannoma 1 trial
- Childhood oligodendroglioma 1 trial
- Extrarenal rhabdoid tumor 1 trial
- Childhood botryoid rhabdomyosarcoma 0 trials Sub-types →
- Childhood cerebral astrocytoma 0 trials Sub-types →
- Childhood epithelioid sarcoma 0 trials
- Childhood malignant melanoma 0 trials Sub-types →
- Childhood malignant mesenchymoma 0 trials
- Childhood pleomorphic rhabdomyosarcoma 0 trials
- Pediatric angiosarcoma 0 trials
- Pediatric extraocular retinoblastoma 0 trials
- Pediatric infratentorial ependymoma 0 trials
- Pediatric liposarcoma 0 trials
- Pediatric mesenchymal chondrosarcoma 0 trials
- Pediatric myxoid chondrosarcoma 0 trials
- Pediatric supratentorial ependymoma 0 trials
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Childhood infratentorial neoplasm 1 trial · 110 incl. sub-types
4 sub-types
- Childhood brain stem neoplasm 3 trials · 95 incl. sub-types Sub-types →
- Childhood cerebellar neoplasm 0 trials · 15 incl. sub-types Sub-types →
- Pediatric infratentorial ependymoblastoma 0 trials
- Pediatric infratentorial ependymoma 0 trials
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Childhood kidney neoplasm 1 trial · 30 incl. sub-types
3 sub-types
- Childhood malignant kidney neoplasm 0 trials · 30 incl. sub-types Sub-types →
- Childhood multilocular cystic kidney neoplasm 0 trials · 1 incl. sub-types Sub-types →
- Childhood kidney angiomyolipoma 0 trials
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Childhood ependymoma 7 trials
1 sub-type
- Pediatric supratentorial ependymoma 0 trials
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Childhood germ cell tumor 3 trials · 7 incl. sub-types
4 sub-types
- Malignant childhood germ cell neoplasm 0 trials · 3 incl. sub-types Sub-types →
- Childhood central nervous system germ cell tumor 0 trials · 2 incl. sub-types Sub-types →
- Childhood gonadal germ cell tumor 1 trial · 2 incl. sub-types Sub-types →
- Pediatric ovarian germ cell tumor 0 trials · 2 incl. sub-types Sub-types →
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Childhood astrocytic tumor 1 trial · 2 incl. sub-types
4 sub-types
- Childhood pilocytic astrocytoma 1 trial Sub-types →
- Childhood brainstem astrocytoma 0 trials
- Childhood cerebellar astrocytic neoplasm 0 trials
- Childhood cerebral astrocytoma 0 trials Sub-types →
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Childhood optic nerve glioma 1 trial
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Childhood spinal cord tumor 1 trial
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Childhood choroid plexus neoplasm 0 trials · 1 incl. sub-types
1 sub-type
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Childhood carcinoid tumor 0 trials
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Childhood testicular neoplasm 0 trials
1 sub-type
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Pediatric meningioma 0 trials
2 sub-types
- Childhood brain meningioma 0 trials
- Pediatric leptomeningeal melanoma 0 trials
Most studied deeper sub-types
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Immune cell boost shows promise against childhood cancers
Disease control CompletedThis early-phase trial tested whether giving activated natural killer (NK) cells, with or without a protein called rhIL15, is safe and feasible for children and young adults with solid tumors that didn't respond to other treatments. Sixteen participants received chemotherapy to l…
Phase 1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Sep 03, 2026 00:00 UTC
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New combo therapy shows promise for hard-to-treat childhood cancers
Disease control CompletedThis early-stage study tested a mix of two drugs (pembrolizumab and decitabine) plus targeted radiation in 22 children and young adults whose solid tumors or lymphoma had returned or stopped responding to treatment. The main goals were to see if the combination was safe and toler…
Early phase 1 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Simple skin care may shield kids from cancer drug side effects
Symptom relief CompletedThis study tested a preventive skin care routine in 14 children (ages 6 months to 18 years) with brain tumors who were receiving targeted therapy (BRAF, MEK, or Pan-RAF inhibitors). The goal was to see if gentle skin care and sun protection could reduce or prevent skin reactions …
Phase 2 • Sponsor: Dana-Farber Cancer Institute • Aim: Symptom relief
Last updated Jun 27, 2026 13:05 UTC
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New online program eases Kids' cancer return to school
Symptom relief CompletedThis study tested a web-based program to help children aged 8-17 with cancer adjust to returning to school. The program included modules for children, parents, teachers, and peers, focusing on communication, coping, and social skills. Twenty children participated, and researchers…
Sponsor: Gazi University • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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Can a Child's cancer be inherited? new study digs into family DNA
Knowledge-focused CompletedThis study looks at the DNA of 100 children (and young adults up to age 17) who have cancer, along with the DNA of their healthy parents. The goal is to find genetic changes that may have caused the cancer. By comparing the child's DNA to both parents', researchers hope to discov…
Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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Personalized medicine for kids with tough cancers: genetic profiling may point to better treatments
Knowledge-focused CompletedThis study looked at whether analyzing the DNA and RNA of children's relapsed or treatment-resistant tumors can help doctors pick targeted therapies. Researchers profiled tumors from 791 children and adolescents using advanced genetic sequencing. The goal was to see how many pati…
Sponsor: Gustave Roussy, Cancer Campus, Grand Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Child cancer and birth defects: hidden genetic clues?
Knowledge-focused CompletedThis completed study collected information from nearly 1,000 children who had both cancer and developmental abnormalities like birth defects or growth issues. The goal was to find new genetic syndromes that make children more likely to develop cancer. Researchers analyzed blood a…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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AI model predicts brain fog risk in kids after tumor surgery
Knowledge-focused CompletedThis study looked at medical records of 600 children who had brain tumor surgery to find out which kids might have long-term thinking or memory problems. Researchers used machine learning to create a tool that predicts this risk based on brain scans, tumor details, and treatment …
Sponsor: West China Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC