New combo therapy shows promise for young cancer patients who have relapsed
NCT ID NCT03445858
First seen Jan 25, 2026 · Last updated May 20, 2026 · Updated 15 times
Summary
This early-phase study tested a combination of two drugs (pembrolizumab and decitabine) plus targeted radiation in 22 children and young adults (ages 1 to 40) with relapsed or refractory solid tumors or lymphoma that had not responded to standard treatments. The main goals were to see if the combination was safe and tolerable, and to get an early look at whether it could shrink tumors. The study was completed, but results are not yet widely reported.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229, United States
Conditions
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