Arthritic joint disease
MONDO:0005578An inflammatory process affecting a joint. Causes include infection, autoimmune processes, degenerative processes, and trauma. Signs and symptoms may include swelling around the affected joint and pain.
Also known as: arthritis, inflammation of skeletal joint, skeletal joint inflammation, inflammatory disorder of joint
2557 clinical trials for this condition and its sub-types, 195 tagged with Arthritic joint disease itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Arthritic joint disease
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Osteoarthritis 685 trials · 1,644 incl. sub-types
5 sub-types
- Osteoarthritis, knee 1,081 trials
- Osteoarthritis, hip 242 trials
- Osteoarthritis, hand 69 trials
- Osteoarthritis, spine 13 trials
- Osteoarthritis, toe 9 trials
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Rheumatoid arthritis 578 trials · 797 incl. sub-types
7 sub-types
- Psoriatic arthritis 188 trials · 201 incl. sub-types Sub-types →
- Ankylosing spondylitis 110 trials · 114 incl. sub-types Sub-types →
- Rheumatoid arthritis-associated interstitial lung disease 12 trials
- Chronic childhood arthritis 5 trials
- Felty syndrome 0 trials
- Polyarticular juvenile rheumatoid arthritis 0 trials
- Rheumatoid vasculitis 0 trials
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Juvenile idiopathic arthritis 107 trials · 115 incl. sub-types
6 sub-types
- Systemic-onset juvenile idiopathic arthritis 25 trials
- Polyarticular juvenile idiopathic arthritis 14 trials · 16 incl. sub-types Sub-types →
- Psoriasis-related juvenile idiopathic arthritis 15 trials
- Enthesitis-related juvenile idiopathic arthritis 7 trials
- Oligoarticular juvenile idiopathic arthritis 5 trials Sub-types →
- Unspecified juvenile idiopathic arthritis 0 trials
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Infective arthritis 25 trials · 100 incl. sub-types
2 sub-types
- Bacterial arthritis 24 trials · 94 incl. sub-types Sub-types →
- Infectious discitis 4 trials Sub-types →
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Synovitis 15 trials
1 sub-type
- Gonococcal synovitis 0 trials
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Adult-onset Still disease 12 trials
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Polyarticular arthritis 11 trials
2 sub-types
- Juvenile chronic polyarthritis 0 trials
- Rheumatoid nodulosis 0 trials
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Hemophilic arthropathy 7 trials
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Chondrocalcinosis 5 trials · 7 incl. sub-types
3 sub-types
- Chondrocalcinosis due to apatite crystal deposition 2 trials
- Chondrocalcinosis 1 0 trials
- Chondrocalcinosis 2 0 trials
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Reactive arthritis 6 trials
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Periarthritis 1 trial
1 sub-type
- Acute calcific periarthritis 0 trials
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Transient arthritis 0 trials
Most studied deeper sub-types
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Knee osteoarthritis drug trial halted early – what we know
Disease control Stopped earlyThis study tested an experimental drug called LNA043, given as injections into the knee, to see if it could slow cartilage loss and reduce pain in people with knee osteoarthritis. The trial planned to follow 576 participants for up to 5 years, but it was terminated early. The mai…
Phase 2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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CBD-Hydroxychloroquine combo tested for arthritis pain – but trial ends early
Disease control Stopped earlyThis study tested a combination pill called IHL-675A, which contains cannabidiol (CBD) and hydroxychloroquine, in people with rheumatoid arthritis. The goal was to see if it safely reduces pain and improves daily function. The trial planned to enroll 128 volunteers but was termin…
Phase 2 • Sponsor: Incannex Healthcare Ltd • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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Can methotrexate replace steroids for immunotherapy joint pain?
Disease control Stopped earlyThis study tested methotrexate, a common arthritis drug, for treating joint pain and swelling caused by cancer treatments that boost the immune system. The goal was to help patients stop taking steroids like prednisone, which have many side effects. The trial was stopped early af…
Phase 2 • Sponsor: AHS Cancer Control Alberta • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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New drug peresolimab tested for rheumatoid arthritis – study ends early
Disease control Stopped earlyThis study tested peresolimab, an experimental drug, in 491 adults with moderately-to-severely active rheumatoid arthritis who had not responded well to other treatments. The goal was to see if peresolimab could reduce joint pain and swelling better than a placebo. However, the s…
Phase 2 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Fat cell injection for arthritis? small study ends early
Disease control Stopped earlyThis study tested whether injecting a person's own fat-derived stem cells into arthritic joints could safely reduce pain and improve movement. Only 14 people with osteoarthritis of the knee, hip, ankle, shoulder, or wrist took part before the study was stopped early. The results …
Sponsor: Sanford Health • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Blood test may predict need for hip revision surgery
Diagnosis Stopped earlyThis study aimed to develop a biomarker test using blood or joint fluid to detect tissue damage (necrosis) caused by metal-on-metal hip implants. Researchers planned to enroll 174 patients, including those needing revision surgery and a control group. The goal was to see if the t…
Sponsor: OrthoCarolina Research Institute, Inc. • Aim: Diagnosis
Last updated Jun 27, 2026 12:37 UTC
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Lyme arthritis pain study halted early – what we know
Symptom relief Stopped earlyThis study aimed to see if taking NSAIDs (like naproxen) on a regular schedule could reduce arthritis symptoms and prevent long-term joint problems in people with Lyme disease. Only 3 participants were enrolled before the study was stopped, so no clear conclusions can be drawn. T…
Phase 3 • Sponsor: Desiree Neville, MD • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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Nickel allergy and knee surgery: no big difference found?
Knowledge-focused Stopped earlyThis study looked at whether people with nickel allergy do better with special nickel-free knee implants. Researchers compared standard implants to nickel-free ones in 9 patients with self-reported nickel sensitivity. The goal was to see if nickel allergy affects pain, function, …
Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Scientists hunt for clues to tell infection apart from inflammation in Kids' joints
Knowledge-focused Stopped earlyThis study looked for new markers in blood and joint fluid to help doctors tell the difference between septic arthritis (a joint infection) and juvenile idiopathic arthritis (an inflammatory condition) in children. Researchers planned to analyze samples from 100 children under 15…
Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Shoulder surgery showdown: onlay vs. inlay – which works better?
Knowledge-focused Stopped earlyThis study looked at two different ways surgeons place the top part of a reverse shoulder replacement: sitting on top of the bone (onlay) or set into the bone (inlay). The goal was to see if one method leads to better arm movement after surgery. The study enrolled 19 people with …
Sponsor: Corewell Health East • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC