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Scientists hunt for clues to tell infection apart from inflammation in Kids' joints

NCT ID NCT03827759

Knowledge-focused Sponsor: University Hospital, Montpellier Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked for new markers in blood and joint fluid to help doctors tell the difference between septic arthritis (a joint infection) and juvenile idiopathic arthritis (an inflammatory condition) in children. Researchers planned to analyze samples from 100 children under 15 with acute arthritis. The study was terminated early, so results may be limited.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

100 people

The number who actually took part.

Started

Feb 2019

Finished

Jul 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Subjects of more than 6 months and under age 15 years, presenting acute arthritis, and control subjects

Ages

6 months to 14 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Group A and group B: * Subject of more than 6 months and under age 15 years, * Presenting acute arthritis taken care in the University Hospitals of Montpellier, Nimes, Toulouse or Lyon, and requiring an articular puncture, * Child benefiting from a social security system, * Collection of the consent of the legal parents/representatives, Group C: * Subject of more than 6 months and under age 15 include, * Taken care in the University Hospital of Montpellier, and requiring a venous draining, * Child benefiting from a social security system, * Collection of the consent of the legal parents/representatives Exclusion Criteria: Group A and group B: * Contraindication in an articular draining: platelet 50 000/mm3, pathologic hemostasis * Treatment by biological therapy, corticoids or other immunosuppressant treatment in the month preceding the articular draining, * antibiotic begun more than 24 hours before the inclusion. Group C: * Patient achieves of an inflammatory chronic pathology * Patient having presented an infectious episode in the previous 8 days * Patients under immunosuppressor or anti-infective

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Conditions

The condition(s) this trial relates to.

arthritic joint disease bacterial arthritis infective arthritis juvenile idiopathic arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Children Inflammatory arthritis Septic arthritis

Contacts and locations

Locations

  • CHU Montpellier - Pediatric emergencies

    Montpellier, Hérault, 34295, France

  • CHU Nîmes - Pediatrics

    Nîmes, 30029, France

  • CHU Toulouse - Pediatric infectious diseases

    Toulouse, 31300, France

  • Hospices Civils de Lyon - pediatric rheumatology

    Lyon, 69002, France

  • Hôpital Saint Joseph

    Marseille, 13285, France

More trials for these conditions

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