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Fat cell injection for arthritis? small study ends early

NCT ID NCT04405297

First seen Nov 01, 2025 · Last updated Jun 20, 2026 · Updated 28 times

Summary

This study tested whether injecting a person's own fat-derived stem cells into arthritic joints could safely reduce pain and improve movement. Only 14 people with osteoarthritis of the knee, hip, ankle, shoulder, or wrist took part before the study was stopped early. The results are too limited to draw any firm conclusions about safety or effectiveness.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Sanford Orthopedics and Sports Medicine

    Sioux Falls, South Dakota, 57104, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

adipose-derived regenerative cells (stromal vascular fraction from fat tissue)

What this could lead to

If it worked, this approach might offer a way to reduce osteoarthritis pain and improve joint function without surgery.

What could go wrong

The trial was terminated early with only 14 participants, so results are very limited. It is unclear if the treatment is safe or effective, and it may not work for all joints.

Conditions

The condition(s) this trial relates to.

arthritic joint disease arthropathy osteoarthritis osteoarthritis, hip osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.