Could ambien help you heal faster after back surgery?

NCT ID NCT05746143

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether taking zolpidem (Ambien) before and after lumbar spine fusion surgery can reduce pain and improve function. 140 adults with degenerative lumbar disease will receive either zolpidem or a placebo. Researchers will measure pain levels and disability up to 6 months after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
zolpidem (Ambien)
What this could lead to
If it works, this could point toward a simple way to improve recovery and reduce pain after spine surgery.
What could go wrong
This is a small, early-phase trial. Zolpidem may not improve outcomes and could cause side effects like drowsiness or confusion.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Keck Medical Center of USC

    RECRUITING

    Los Angeles, California, 90033, United States

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Other studies related to the condition(s) this trial covers.