WISH upon a gut: can optimism ease IBS?

NCT ID NCT06866106

Recruiting now Symptom relief Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a 9-week phone-based program called WISH that teaches positive psychology exercises to people with irritable bowel syndrome (IBS). The goal is to see if the program is practical and helpful for improving symptoms. Researchers will compare it to an educational control group and look at how it affects the gut-brain connection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Positive psychology (PP) intervention (behavioral)
What this could lead to: If it works, this could offer a simple, phone-based way to help IBS patients feel better by boosting optimism and reducing stress.
What could go wrong: This is a small, early feasibility study with only 50 people. It's not designed to prove the treatment works, and results may not apply to everyone with IBS.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

irritable bowel syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IRRITABLE BOWEL SYNDROME

Contacts and locations

Locations

Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States

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