Brain protein may reveal who will regain weight after stopping popular weight loss drugs

NCT ID NCT06795360

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 52 adults who are about to stop taking injectable weight loss drugs due to insurance changes. Researchers will measure a brain protein called Agouti-related peptide (AgRP) and track weight changes over 3 months. The goal is to see if this protein can predict who will regain weight after stopping the medication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

discontinuation of weight loss medication

What this could lead to

If successful, this could help identify people at risk of regaining weight after stopping injectable weight loss drugs, allowing for better personalized care.

What could go wrong

This is a small observational study with only 52 participants, so results may not apply to everyone. It only looks at a 3-month period, so longer-term effects are unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Weight Gain Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••