Heart mapping study seeks clues to dangerous rhythms in genetic AF patients

NCT ID NCT06647459

Terminated Knowledge-focused Sponsor: Vanderbilt University Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aimed to understand why some people with genetic early-onset atrial fibrillation (AF) are at risk for a dangerous heart rhythm called ventricular tachycardia (VT). Researchers used special heart mapping during a standard AF ablation procedure in 32 adults. The goal was to compare heart tissue and electrical patterns between those with a specific genetic variant (TTN) and those without, to better predict VT risk.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors better predict dangerous heart rhythms in people with certain genetic forms of atrial fibrillation.
What could go wrong: This trial was terminated early with only 32 participants, so results may be limited. It is an observational mapping study, not a treatment test.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation ventricular tachycardia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION VENTRICULAR TACHYCARDIA

Contacts and locations

Locations

Vanderbilt University Medical Center

Nashville, Tennessee, 37232, United States

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