When to add a second blood pressure drug in septic shock? large trial seeks answers

NCT ID NCT06217562

Completed Disease control Sponsor: Intermountain Health Care, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Aug 04, 2026 · Updated 4 times

Summary

This study looks at the best time to add the drug vasopressin for people with septic shock—a life-threatening drop in blood pressure from infection. About 2,050 adults will be treated using either an earlier or later threshold for starting vasopressin. The goal is to see which approach reduces deaths within 28 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Vasopressin (a drug that raises blood pressure)
What this could lead to: If successful, this could help doctors know the best time to add vasopressin to treat septic shock, potentially saving more lives.
What could go wrong: This is a late-stage trial but compares two common strategies, so the difference may be small. Results may not apply to all hospitals or patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

diabetes insipidus toxic shock syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SEPTIC SHOCK

Contacts and locations

Locations

Alta View Hospital

Sandy City, Utah, 84094, United States
American Fork Hospital

American Fork, Utah, 84003, United States
Cassia Regional Hospital

Burley, Idaho, 83318, United States
Cedar City Hospital

Cedar City, Utah, 84721, United States
Intermountain Medical Center

Murray, Utah, 84107, United States
LDS Hospital

Salt Lake City, Utah, 84143, United States
Layton Hospital

Layton, Utah, 84041, United States
Logan Regional Hospital

Logan, Utah, 84341, United States
McKay-Dee Hospital

Ogden, Utah, 84403, United States
Park City Hospital

Park City, Utah, 84060, United States
Riverton Hospital

Riverton, Utah, 84065, United States
St. George Regional Hospital

St. George, Utah, 84790, United States
Utah Valley Hospital

Provo, Utah, 84604, United States

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