When to add a second blood pressure drug in septic shock? large trial seeks answers

NCT ID NCT06217562

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looks at the best time to add the drug vasopressin for people with septic shock—a life-threatening drop in blood pressure from infection. About 2,050 adults will be treated using either an earlier or later threshold for starting vasopressin. The goal is to see which approach reduces deaths within 28 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Vasopressin (a drug that raises blood pressure)

What this could lead to

If successful, this could help doctors know the best time to add vasopressin to treat septic shock, potentially saving more lives.

What could go wrong

This is a late-stage trial but compares two common strategies, so the difference may be small. Results may not apply to all hospitals or patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diabetes insipidus toxic shock syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Alta View Hospital

    Sandy City, Utah, 84094, United States

  • American Fork Hospital

    American Fork, Utah, 84003, United States

  • Cassia Regional Hospital

    Burley, Idaho, 83318, United States

  • Cedar City Hospital

    Cedar City, Utah, 84721, United States

  • Intermountain Medical Center

    Murray, Utah, 84107, United States

  • LDS Hospital

    Salt Lake City, Utah, 84143, United States

  • Layton Hospital

    Layton, Utah, 84041, United States

  • Logan Regional Hospital

    Logan, Utah, 84341, United States

  • McKay-Dee Hospital

    Ogden, Utah, 84403, United States

  • Park City Hospital

    Park City, Utah, 84060, United States

  • Riverton Hospital

    Riverton, Utah, 84065, United States

  • St. George Regional Hospital

    St. George, Utah, 84790, United States

  • Utah Valley Hospital

    Provo, Utah, 84604, United States