New hope for veterans who smoke: a drug to help cut down without quitting first
NCT ID NCT06966362
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether the drug varenicline (Chantix) can help veterans who smoke at least 5 cigarettes a day but aren't ready to quit. Participants will either take varenicline or use nicotine lozenges to reduce smoking over 12 weeks. The goal is to see if this approach leads to more quit attempts and long-term abstinence. The trial will involve 400 veterans across the U.S.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Varenicline (Chantix) and nicotine mini-lozenge
What this could lead to
If successful, this could provide an effective way to help veterans who are not ready to quit smoking reduce their smoking and eventually quit, lowering their risk of smoking-related diseases.
What could go wrong
This is a phase 4 trial, so the drug is already approved, but it's testing a new use in a specific group. The results may not apply to all smokers, and side effects like nausea or sleep problems are possible.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Durham VA Medical Center, Durham, NC
Durham, North Carolina, 27705-3875, United States
Contact Email: •••••@•••••
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Minneapolis VA Health Care System, Minneapolis, MN
Minneapolis, Minnesota, 55417-2309, United States
Contact Email: •••••@•••••
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VA San Diego Healthcare System, San Diego, CA
San Diego, California, 92161-0002, United States
Contact Email: •••••@•••••
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William S. Middleton Memorial Veterans Hospital, Madison, WI
Madison, Wisconsin, 53705-2254, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact