New calculator could help sick newborns get the right antibiotic dose faster
NCT ID NCT05770622
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests whether using early drug monitoring and a dose-adjustment calculator can help infants under 90 days old with sepsis reach target vancomycin levels more quickly. Currently, doctors must wait 24-48 hours to check drug levels, which can delay effective treatment. The study will enroll 40 infants and use a web-based calculator to adjust doses after the first dose if needed.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
vancomycin
What this could lead to
If successful, this approach could help doctors get the right dose of vancomycin to sick infants faster, potentially improving infection treatment.
What could go wrong
This is a small, early-phase study (40 infants) focused on dosing accuracy, not on curing sepsis. It may not lead to better health outcomes or apply to all infants.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Monash Newborn
NOT_YET_RECRUITINGMelbourne, Australia
Contact
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Royal Children's Hospital Melbourne
RECRUITINGMelbourne, Victoria, 3052, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Royal Hospital for Women
NOT_YET_RECRUITINGSydney, Australia
Contact
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The Children's Hospital at Westmead
RECRUITINGSydney, Australia
Contact