Scientists hunt for genetic clues in bladder cancer samples

NCT ID NCT02379429

First seen Jun 26, 2026 · Last updated Aug 12, 2026 · Updated 3 times

Summary

This study collects blood, urine, saliva, and tumor tissue from 500 adults with urothelial cancer (bladder, ureter, or urethra) and healthy volunteers. Researchers will analyze the samples to find genetic differences between normal and cancer cells. The goal is to better understand what causes the cancer and identify new targets for treatment. Participants give samples and have follow-up calls every 6 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this research could reveal genetic changes that drive urothelial cancer, pointing toward new drug targets or better ways to predict treatment response.
What could go wrong
This is an observational sample-collection study, not a treatment trial. It will not directly benefit participants and may not lead to any new therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

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Other studies related to the condition(s) this trial covers.