Scientists dig into mysterious kidney scarring

NCT ID NCT00001392

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study looked at why some people develop scarring in their kidneys, including rare diseases like FSGS and a mysterious form of chronic kidney disease affecting farm workers. Researchers collected blood, urine, and kidney tissue from 537 participants to better understand what causes these conditions. The goal was to generate new ideas for future treatments, not to test a specific drug.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could point toward new treatment targets for chronic kidney diseases like FSGS and CKDu.

What could go wrong

This is an observational study, not a treatment trial. It aims to generate hypotheses, not test a cure, so direct patient benefits are uncertain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease focal segmental glomerulosclerosis glomerular disorder viral infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States