Scientists dig into mysterious kidney scarring

NCT ID NCT00001392

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 5 times

Summary

This completed study looked at why some people develop scarring in their kidneys, including rare diseases like FSGS and a mysterious form of chronic kidney disease affecting farm workers. Researchers collected blood, urine, and kidney tissue from 537 participants to better understand what causes these conditions. The goal was to generate new ideas for future treatments, not to test a specific drug.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this research could point toward new treatment targets for chronic kidney diseases like FSGS and CKDu.
What could go wrong
This is an observational study, not a treatment trial. It aims to generate hypotheses, not test a cure, so direct patient benefits are uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.