Higher voltage nerve zap may ease chronic migraine

NCT ID NCT07500558

Recruiting now Symptom relief Sponsor: Minia University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether using a higher voltage during a nerve-blocking procedure (pulsed radiofrequency) can better relieve pain in people with chronic migraine who haven't responded to at least two preventive medications. One hundred participants will be randomly assigned to receive either standard or higher-voltage treatment, guided by ultrasound. The main goal is to see if more people get at least 50% pain reduction with the higher voltage.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: pulsed radiofrequency (standard or higher voltage) applied to the sphenopalatine ganglion
What this could lead to: If it works, this could offer a better, longer-lasting pain relief option for people with chronic migraine who haven't responded to medications.
What could go wrong: This is a small, early-stage trial (100 people) comparing two similar procedures. The higher voltage may not provide extra benefit and could cause discomfort or rare nerve issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CHRONIC MIGRAINE HEADACHE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Headache headache disorder migraine disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC MIGRAINE HEADACHE

Contacts and locations

Locations

Minia university
RECRUITING

Minya, 61511, Egypt
Minia university raouf
RECRUITING

Minya, 61511, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.