Diabetes mystery: why some patients escape complications while others suffer

NCT ID NCT07250607

Ongoing Knowledge-focused Sponsor: Azienda Ospedaliero, Universitaria Pisana Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This observational study is looking at 1,000 people with type 2 diabetes to understand why some develop serious complications like eye, kidney, or heart problems while others do not, even with similar blood sugar levels. Researchers will collect medical history and blood samples to identify biological markers that might predict a person's risk. The goal is to create a simple scoring system to help doctors personalize care and prevent complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a tool that helps doctors identify which patients with type 2 diabetes are at higher risk for complications, allowing for earlier and more personalized care.
What could go wrong: This is an observational study, not a treatment trial. It may not find clear biomarkers or a reliable risk score, and any findings will need further validation before they can be used in practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder Diabetes Complications type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIABETE TYPE 2 DIABETES COMPLICATIONS

Contacts and locations

Locations

Azienda Ospedaliero Universitaria Pisana

Pisa, PI, 56120, Italy
Azienda Rilievo Nazionale Alta Specialità (ARNAS) Garibaldi

Catania, CT, 95100, Italy
Policlinico Consorziale di Bari

Bari, BA, 70100, Italy

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