New hope for advanced breast cancer: drug combo tested after chemo fails

NCT ID NCT04489173

Ongoing Disease control Sponsor: Borstkanker Onderzoek Groep Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 27 times

Summary

This study tests a drug called trifluridine/tipiracil in 52 women with advanced ER-positive, HER2-negative breast cancer that can't be cured with surgery or radiation. Participants had already received certain chemotherapies. The goal is to see if the drug can slow cancer growth and improve quality of life, while monitoring side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Amphia Ziekenhuis

Breda, Netherlands
Catharina Ziekenhuis

Eindhoven, Netherlands
Deventer ziekenhuis

Deventer, Netherlands
Erasmus MC

Rotterdam, Netherlands
MC Leeuwarden

Leeuwarden, Netherlands
MUMC

Maastricht, Netherlands
Reinier de Graaf Groep

Delft, Netherlands
Rijnstate

Arnhem, Netherlands
UMC Utrecht

Utrecht, Netherlands
Wilhelmina ziekenhuis

Assen, Netherlands

Conditions

Explore the condition pages connected to this study.

BREAST NEOPLASM BREAST NEOPLASM CHEMOTHERAPY EFFECT