Borstkanker Onderzoek Groep

This study is testing if adding a drug called alpelisib to the standard hormone therapy fulvestrant can help control advanced breast cancer that has started to grow again on fulvestrant alone. It is for adults whose cancer is hormone-receptor positive, HER2 negative, and has a sp…

This large study aims to find the best sequence for two standard treatments for advanced, hormone-sensitive breast cancer. It will compare starting with a powerful but costly combination drug right away versus saving it for the second line of treatment. The goal is to see which o…

This study is testing a personalized approach to chemotherapy for HER2-positive breast cancer. It aims to see if doctors can safely give fewer chemotherapy cycles to patients who show a strong, early response to treatment on an MRI scan. The goal is to reduce side effects while s…

This study is testing whether the drug trifluridine/tipiracil can help control advanced breast cancer that has stopped responding to standard chemotherapy. It is for women with a specific type (ER-positive, HER2-negative) who have already been treated with two common chemo drugs.…

This study is testing if a combination of two pills (ribociclib and letrozole) can work as well as standard chemotherapy when given before surgery for certain types of breast cancer. It involves 100 postmenopausal women with hormone-sensitive, HER2-negative breast cancer. Doctors…