New scan may spare prostate cancer patients unnecessary surgery
NCT ID NCT06389786
First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 37 times
Summary
This study tests whether a combined PET/MRI scan using a radioactive tracer can accurately detect if prostate cancer has spread to nearby lymph nodes. Fifty men with high-risk localized prostate cancer will receive the scan before their planned prostate removal surgery. The results will be compared to the actual findings from lymph node tissue removed during surgery to see how well the scan predicts spread.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Mayo Clinic in Florida
RECRUITINGJacksonville, Florida, 32224-9980, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
18F-rhPSMA-7.3 (a radioactive tracer for PET imaging)
What this could lead to
If successful, this imaging method could help doctors decide which patients need lymph node removal during prostate cancer surgery, avoiding unnecessary procedures.
What could go wrong
This is a small, early-stage study (50 participants) focused on accuracy, not treatment. The scan may not be accurate enough to replace standard surgery in all cases.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.