Could a Weight-Loss drug stop colon cancer before it starts?

NCT ID NCT07095517

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tests whether tirzepatide, a drug used for diabetes and weight loss, can lower biological markers linked to colorectal cancer risk. Researchers will enroll 20 adults aged 18-50 with a BMI between 27 and 40 who have had a recent colonoscopy. The goal is to see if the drug changes certain substances in urine, blood, and tissue that are associated with cancer development.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Massachusetts General Hospital Cancer Center

    RECRUITING

    Boston, Massachusetts, 02114, United States

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