Could a single dose of testosterone boost nerve function in spinal cord injury?

NCT ID NCT06130449

Recruiting now Knowledge-focused Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase study looks at how a single dose of intranasal testosterone affects nerve and autonomic function in 15 male veterans with spinal cord injury who have low testosterone. Researchers will measure muscle responses and heart rate changes before and after the dose. The goal is to understand if testosterone can improve nerve signaling and autonomic reflexes in this population.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: testosterone intranasal gel
What this could lead to: If it works, this could point toward a way to improve nerve and autonomic function in men with spinal cord injury.
What could go wrong: This is a very early, small study with only 15 participants. It tests a single dose, so any effects may be temporary or not translate to long-term benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SPINAL CORD INJURY

Contacts and locations

Locations

James J. Peters VA Medical Center, Bronx, NY
RECRUITING

The Bronx, New York, 10468-3904, United States

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