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Simple blood test may spot diabetes early in obese kids

NCT ID NCT06682481

Recruiting now Knowledge-focused Sponsor: Philippe Klee, MD-PhD Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a substance in the blood called 1,5-anhydroglucitol can serve as a marker for how well the pancreas is working in obese children, with or without type 2 diabetes. Researchers will measure levels of this marker in 50 children aged 12 to 16 and compare them to healthy volunteers. The goal is to find a simple way to detect early problems with insulin-producing beta cells, which could lead to better monitoring and prevention of diabetes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
1,5-anhydroglucitol (a blood sugar marker)
What this could lead to
If successful, this could provide a simple blood test to detect early beta-cell problems in obese children, helping to prevent or manage type 2 diabetes.
What could go wrong
This is a small, early observational study (50 children) that only measures a biomarker, not a treatment. The marker may not prove reliable enough for clinical use.

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Conditions

The condition(s) this trial relates to.

obesity disorder Pediatric Obesity type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBESITY, CHILDHOOD TYPE 2 DIABETES MELLITUS IN OBESE

Contacts and locations

Locations

  • University Hospital of Geneva

    RECRUITING

    Geneva, Canton of Geneva, 1211, Switzerland

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