New acid blocker tested to make anesthesia safer
NCT ID NCT06743243
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests whether the drug tegoprazan can raise stomach acid levels before general anesthesia better than famotidine or a placebo. 174 adults having elective surgery will receive one of the three treatments an hour before anesthesia. The main goal is to measure stomach pH right after intubation, aiming to lower the risk of acid aspiration.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Tegoprazan
- What this could lead to
- If it works, tegoprazan could become a standard pre-anesthesia medication to reduce the risk of stomach acid entering the lungs during surgery.
- What could go wrong
- This is a small, early-phase trial focused on a lab measurement (gastric pH), not on actual complications. The drug may not show a meaningful benefit over existing options like famotidine.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Korea University Medical Center, Guro Hospital
Seoul, South Korea
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