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New acid blocker tested to make anesthesia safer

NCT ID NCT06743243

Disease control Sponsor: Seok Kyeong Oh Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests whether the drug tegoprazan can raise stomach acid levels before general anesthesia better than famotidine or a placebo. 174 adults having elective surgery will receive one of the three treatments an hour before anesthesia. The main goal is to measure stomach pH right after intubation, aiming to lower the risk of acid aspiration.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Tegoprazan
What this could lead to
If it works, tegoprazan could become a standard pre-anesthesia medication to reduce the risk of stomach acid entering the lungs during surgery.
What could go wrong
This is a small, early-phase trial focused on a lab measurement (gastric pH), not on actual complications. The drug may not show a meaningful benefit over existing options like famotidine.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

About 174 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 69 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Has a plan to undergo surgery with general anesthesia with inhalation or total Intravenous 2. Subjects aged between 20 and 69 years 3. ASA classification I - III Exclusion Criteria: 1. Conduct Emergency surgery 2. BMI(Body Mass Index) ≥ 35 3. Has a history of drug abuse or depandency. 4. Has a history of Anesthetic allergy 5. Has a plan to undergo resection(gastric cancer, esophageal cancer)

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

General anesthesia

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Korea University Medical Center, Guro Hospital

    Seoul, South Korea

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