Genetically modified immune cells take on Hard-to-Treat cancers

NCT ID NCT02869217

First seen Dec 29, 2025 · Last updated May 15, 2026 · Updated 22 times

Summary

This early-phase study tests a treatment called TBI-1301 for people with advanced solid tumors (like sarcoma, melanoma, or ovarian cancer) that have not responded to other therapies. The treatment uses a patient's own immune cells, which are genetically modified in a lab to better recognize and attack cancer cells. The main goal is to check the safety of this approach and find the right dose, with a small group of 22 participants.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Princess Margaret Cancer Centre

    Toronto, Ontario, M5G 2M9, Canada

Conditions

Explore the condition pages connected to this study.