Gene test could make TB prevention safer and more effective

NCT ID NCT05413551

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether adjusting the dose of a tuberculosis (TB) prevention drug based on a person's genetic makeup could improve treatment. Researchers enrolled 78 people and used a quick genetic test to guide the dose of isoniazid. The goal was to see if this personalized approach leads to better drug levels in the body, potentially making TB prevention more effective and reducing side effects.

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Conditions

The condition(s) this trial relates to.

isoniazid toxicity latent tuberculosis infection tuberculosis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Federal University of Mato Grosso do Sul

    Campo Grande, Mato Grosso do Sul, Brazil