Less invasive heart valve replacement may be better for seniors with small valves
NCT ID NCT03383445
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two ways to replace a narrowed heart valve in elderly patients (65+) who have a small valve opening. One method is less invasive (TAVR, through a tube in an artery), the other is open-heart surgery. The goal is to see which approach gives better blood flow and fewer complications like stroke or bleeding. About 300 participants will be randomly assigned to one of the two procedures.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Transcatheter aortic valve replacement (TAVR) or surgical aortic valve replacement (SAVR)
What this could lead to
If TAVR proves better, it could become the preferred, less invasive option for elderly patients with small aortic valves, reducing complications and improving heart function.
What could go wrong
This is a mid-stage trial with 300 participants, so results may not apply to all patients. Both procedures carry risks like bleeding, stroke, or valve mismatch.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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IUCPQ
Québec, Quebec, G1V 4G5, Canada