Ear-Zap therapy could spare kids from harsh kidney drugs

NCT ID NCT05583942

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a noninvasive device that gently stimulates a nerve in the ear to help children with steroid-resistant nephrotic syndrome, a kidney condition that doesn't respond to standard steroids. The goal is to see if this approach is feasible and tolerable, and if it can reduce inflammation and protein in the urine. Ten children aged 3-17 with specific kidney diagnoses will be randomly assigned to real or sham stimulation.

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Conditions

The condition(s) this trial relates to.

focal segmental glomerulosclerosis lipoid nephrosis nephrotic syndrome steroid-resistant nephrotic syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's Hospital of Philadelphia

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Cohen Children's Medical Center

    RECRUITING

    New Hyde Park, New York, 11040, United States

    Contact

    Contact

    Contact

    Contact

    Contact

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••