MINIMAL CHANGE DISEASE

This study tests a noninvasive device that stimulates a nerve in the ear to help children with steroid-resistant nephrotic syndrome, a kidney condition that doesn't respond to standard steroids. The device aims to calm the immune system and reduce inflammation, potentially allowi…

This study tests an investigational drug called WAL0921 in adults with certain kidney diseases that cause protein in the urine. About 96 participants will receive either the drug or a placebo as an IV infusion every two weeks for 14 weeks. The goal is to see if the drug is safe a…

This study tests an oral drug called sparsentan in 67 children with certain kidney diseases that cause protein in the urine. The goal is to see if the drug safely reduces protein leakage and helps control the disease over about two years. Participants take the drug once daily, an…

This small pilot study is testing whether a gentle, non-invasive nerve stimulation device worn on the ear can help children with a frequently relapsing kidney disease. The goal is to see if this approach can reduce disease flare-ups and the need for strong steroid medications. Re…

This study helps people with certain kidney diseases (like nephrotic syndrome and FSGS) find clinical trials that might be a good fit for their specific condition. Researchers use advanced molecular testing to match each person's unique disease profile to targeted therapies being…

This study is gathering information and biological samples from 300 people with FSGS or MCD who have had or will have a kidney transplant. Researchers want to learn why the disease sometimes comes back after transplant, which can lead to graft loss. The goal is to create a shared…

This study interviews 150 children, adults, and parents about their experiences with swelling caused by Nephrotic Syndrome. Researchers will use the information to create a survey that helps test new medications. No treatment is given; the goal is to better understand symptoms.

This study is creating a registry of 500 people with two rare kidney diseases—FSGS and minimal change disease—to track their health over 10 years. Researchers will collect blood, urine, and tissue samples to better understand what causes these conditions and how they progress. Th…