New drug aims to slow kidney damage in diabetes and rare diseases
NCT ID NCT06466135
First seen Jun 27, 2026 · Last updated Aug 04, 2026 · Updated 2 times
Summary
This study tests an experimental drug called WAL0921 in 96 adults with kidney diseases that cause protein in the urine, including diabetic nephropathy and several rare conditions. Participants receive either the drug or a placebo as an IV infusion every two weeks for 14 weeks, then are monitored for 24 more weeks. The goal is to see if the drug is safe and can reduce protein leakage and protect kidney function.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
Locations
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AIIMS Hospital
ACTIVE_NOT_RECRUITINGRaipur, Chhattisgarh, 492099, India
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Academic Medical Research Institute
RECRUITINGLos Angeles, California, 90022, United States
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Ajou University Hospital
RECRUITINGSuwon, 16499, South Korea
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Barts Health NHS Trust
WITHDRAWNLondon, E1 2ES, United Kingdom
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Clinical Advancement Center
RECRUITINGSan Antonio, Texas, 78212, United States
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Clinical Trial Network
RECRUITINGHouston, Texas, 77074, United States
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College of Life Sciences, University of Leicester
RECRUITINGLeicester, LE1 7RH, United Kingdom
Contact Email: •••••@•••••
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Colorado Kidney and Vascular Care
RECRUITINGDenver, Colorado, 80012, United States
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D & H Tamarac Research Center
RECRUITINGTamarac, Florida, 33321, United States
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Dhiraj Hospital
ACTIVE_NOT_RECRUITINGVadodara, Gujarat, 391760, India
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Dunes Clinical Research
RECRUITINGDakota Dunes, South Dakota, 57049, United States
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Fides Clinical Research
RECRUITINGAtlanta, Georgia, 30342, United States
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Hallym University Sacred Heart Hospital
RECRUITINGAnyang, 14068, South Korea
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Hospital Canselor Tuanku Muhriz UKM
RECRUITINGCheras, Kuala Lumpur, 56000, Malaysia
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Hospital Kuala Lumpur
RECRUITINGKuala Lumpur, Kuala Lumpur, 50586, Malaysia
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Hospital Sultan Idris Shah Serdang
RECRUITINGKajang, Selangor, 43000, Malaysia
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Hospital Tengku Ampuan Afzan
RECRUITINGKuantan, Pahang, 25100, Malaysia
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Jaffna Teaching Hospital
NOT_YET_RECRUITINGJaffna, 40000, Sri Lanka
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Kandy National Hospital
NOT_YET_RECRUITINGKandy, 20000, Sri Lanka
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Kothalawala Defence University Hospital
NOT_YET_RECRUITINGWerahera, 10290, Sri Lanka
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Kurunegala Teaching Hospital
NOT_YET_RECRUITINGKurunegala, 60000, Sri Lanka
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MGM Medical Care and Hospital
ACTIVE_NOT_RECRUITINGSambhajinagar, Maharashtra, 431003, India
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MS Ramaiah Medical College and Hospitals
ACTIVE_NOT_RECRUITINGBangalore, Karnataka, 560054, India
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Manchester University NHS Foundation Trust
NOT_YET_RECRUITINGManchester, M13 9WL, United Kingdom
Contact Email: •••••@•••••
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Manipal Hospital
ACTIVE_NOT_RECRUITINGPune, Maharashtra, 411045, India
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Max Super Speciality Hospital
ACTIVE_NOT_RECRUITINGPatparganj, National Capital Territory of Delhi, 110092, India
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Mazumdar Shah Medical Center
ACTIVE_NOT_RECRUITINGBangalore, Karnataka, 560099, India
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Muljibhai Patel Urological Hospital
ACTIVE_NOT_RECRUITINGNadiād, Gujarat, 387003, India
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NRS Medical College and Hospital Kolkata
ACTIVE_NOT_RECRUITINGKolkata, West Bengal, 700014, India
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National Hospital of Sri Lanka
NOT_YET_RECRUITINGColombo, 00700, Sri Lanka
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Nephrology Associates of Northern Illinois and Indiana (NANI)
RECRUITINGHinsdale, Illinois, 60521, United States
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Nizam's Institute of Medical Sciences
ACTIVE_NOT_RECRUITINGHyderabad, Telangana, 500082, India
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Nutema Hospital
ACTIVE_NOT_RECRUITINGMeerut, Uttar Pradesh, 250002, India
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Osmania General Hospital
ACTIVE_NOT_RECRUITINGHyderabad, Telangana, 500012, India
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Prolato Clinical Research Center
RECRUITINGHouston, Texas, 77054, United States
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Pusan National University Hospital
RECRUITINGBusan, 49241, South Korea
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Royal Derby Hospital
RECRUITINGDerby, DE22 3NE, United Kingdom
Contact Email: •••••@•••••
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SMS Medical College and Hospital
ACTIVE_NOT_RECRUITINGJaipur, Rajasthan, 302004, India
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SUM Hospital
ACTIVE_NOT_RECRUITINGBhubaneswar, Odisha, 751029, India
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Salford Royal NHS Foundation Trust
NOT_YET_RECRUITINGSalford, M6 8HD, United Kingdom
Contact Email: •••••@•••••
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Samsung Medical Center
RECRUITINGSoeul, 06351, South Korea
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Sanjay Gandhi Post Graduate Institute of Medical Sciences
ACTIVE_NOT_RECRUITINGLucknow, Uttar Pradesh, 226014, India
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Seoul National University Bundang Hospital
RECRUITINGSeongnam-si, 13620, South Korea
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Severance Hospital - Yonsei Cancer Center
RECRUITINGSeoul, 03722, South Korea
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Shri Guru Ram Rai Institute of Medical and Health Sciences
ACTIVE_NOT_RECRUITINGDehradun, Uttarakhand, 248001, India
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Sir Ganga Ram Hospital
ACTIVE_NOT_RECRUITINGNew Delhi, National Capital Territory of Delhi, 110060, India
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Sunway Medical Centre
RECRUITINGPetaling Jaya, Selangor, 47500, Malaysia
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University Malaya Medical Centre
RECRUITINGKuala Lumpur, Kuala Lumpur, 50603, Malaysia
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Western Health Sunshine Hospital
RECRUITINGSt Albans, Victoria, 3021, Australia
Contact Email: •••••@•••••
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Westmead Hospital
RECRUITINGWestmead, New South Wales, 2145, Australia
Contact Email: •••••@•••••
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Other studies related to the condition(s) this trial covers.
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- One infusion, two targets: a uric-acid-lowering drug takes aim at heart and kidney disease in youth-onset diabetes