Radioactive tracer reveals tau tangles in Alzheimer's brains
NCT ID NCT02414178
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new radioactive compound called F 18 T807 that lights up tau tangles in the brain during a PET scan. Researchers want to see if the amount of tau relates to memory and thinking problems in people with a rare, inherited form of Alzheimer's disease. About 130 adults with or without mild dementia will get one injection and a brain scan. The goal is to better understand how tau buildup affects the mind, not to treat the disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
F 18 T807 (a radioactive tracer for PET scans)
What this could lead to
If successful, this could help doctors detect Alzheimer's earlier and track disease progression using brain scans.
What could go wrong
This is an early imaging study, not a treatment trial. The tracer is not FDA-approved, and it may not reliably predict cognitive decline.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Washington University School of Medicine
St Louis, Missouri, 63110, United States