New embolization technique could offer knee pain relief without surgery
NCT ID NCT07140367
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a procedure called transarterial microembolization (TAME) for people with knee osteoarthritis and long-lasting pain that hasn't improved with standard treatments. Doctors will inject tiny beads into blood vessels around the knee to block abnormal blood flow, aiming to reduce pain and improve quality of life. Forty-three participants will be followed for up to two years to see if the procedure works and is safe.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Transarterial microembolization (TAME) procedure using Nexsphere-F embolic beads
What this could lead to
If it works, this could offer a new, less invasive option to ease chronic knee pain and delay or avoid knee replacement surgery.
What could go wrong
This is a small, early observational study with only 43 participants and no comparison group, so results may not apply broadly. The procedure carries risks like bleeding, infection, or incomplete pain relief.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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IRCCS Istituto Ortopedico Rizzoli
RECRUITINGBologna, Bologna, 40136, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••