New combo therapy targets breast cancer brain tumors

NCT ID NCT07454668

First seen Mar 08, 2026 · Last updated May 12, 2026 · Updated 7 times

Summary

This early-phase study tests a targeted drug (trastuzumab deruxtecan) combined with precise radiation (stereotactic radiosurgery) in 20 people with HER2-positive breast cancer that has spread to the brain. The goal is to find the safest drug dose and see how well the combination controls brain tumors. Participants must have 1 to 10 small brain metastases and be in good overall health.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BREAST CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Miami Cancer Institute at Baptist Health, Inc.

    Miami, Florida, 33176, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.