CANCER METASTATIC

This early-phase study tests a new drug called INV-1120, either by itself or combined with pembrolizumab (Keytruda), in adults with advanced solid tumors that have stopped responding to standard treatments. The main goals are to find safe doses and check for side effects. About 7…

This study looks at how well a special implant (IlluminOss) works to reduce pain and improve daily function in people with pelvic fractures caused by cancer spread or aging. About 100 adults will receive the implant as part of their normal care and will report their pain and mobi…

This study tests whether a newer, more precise type of radiation (SBRT) provides better pain relief than standard radiation for people with cancer that has spread to bones other than the spine. About 230 adults with solid tumors and painful bone metastases will be randomly assign…

This study creates a registry of 500 children, teens, and young adults (up to age 39) diagnosed with cancer. Participants fill out surveys, do physical and thinking tests, and give blood or other samples at diagnosis, during treatment, and yearly after. The goal is to learn how c…

This study is testing whether an artificial intelligence (AI) tool can help match people with advanced cancer to the right clinical trials. Researchers will enroll up to 50,000 participants to see if the AI improves trial enrollment rates and patient outcomes. The goal is to make…