Can a common eye supplement fight cancer? new trial begins

NCT ID NCT05232409

First seen Jun 05, 2026 · Last updated Jun 23, 2026 · Updated 4 times

Summary

This early-stage trial is testing whether a dietary supplement called zeaxanthin, taken alone or with the immunotherapy drug pembrolizumab, is safe for people with advanced solid tumors that have not responded to standard treatments. The study will enroll 72 participants to find the highest safe dose and check for side effects. It does not aim to cure cancer at this point, but to lay the groundwork for future studies.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Valley Hospital-Luckow Pavilion

    RECRUITING

    Paramus, New Jersey, 07652, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

zeaxanthin (a dietary supplement) alone or combined with pembrolizumab (an immunotherapy drug)

What this could lead to

If it works, this could point toward a new treatment option for advanced cancers that have not responded to standard therapies.

What could go wrong

This is a very early phase 1 trial focused on safety and dosing, not effectiveness. The supplement may not shrink tumors or may cause side effects. Success is uncertain.

Conditions

The condition(s) this trial relates to.

metastatic malignant neoplasm Neoplasm Metastasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.