New obesity drug switch trial aims to keep weight off Long-Term

NCT ID NCT07575399

Not yet recruiting Disease control Sponsor: Amgen Source: ClinicalTrials.gov ↗

First seen May 14, 2026 · Last updated May 14, 2026

Summary

This study tests whether switching from popular weight-loss drugs (GLP-1 receptor agonists) to a new medication called maridebart cafraglutide can help adults with obesity or overweight maintain weight loss. About 300 participants who have already lost at least 10% of their body weight on a GLP-1 drug will be enrolled. The main goal is to see how body weight changes over 68 weeks, along with safety and tolerability.

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