New Non-Addictive pain drug could curb opioid dependence after surgery
NCT ID NCT07672015
First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times
Summary
This study tests whether suzetrigine, a non-opioid painkiller, can help patients who are at high risk for long-term opioid use after surgery. About 100 people having major orthopedic surgery will be randomly assigned to receive either standard pain care or standard care plus suzetrigine for 14 days. The main goal is to see if suzetrigine reduces the total amount of opioids taken after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Suzetrigine (Journavx), a non-opioid painkiller
What this could lead to
If successful, this could offer a safer, non-addictive way to manage post-surgery pain and reduce the risk of long-term opioid use.
What could go wrong
This is a small, early-phase trial with only 100 participants, so results may not apply to everyone. The drug may not reduce opioid use as hoped.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of California, San Diego
La Jolla, California, 92037, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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