Could a weekly shot tackle fatty liver and obesity?

NCT ID NCT06309992

Completed Disease control Sponsor: Boehringer Ingelheim Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a medicine called survodutide in adults with overweight or obesity and a liver condition called NASH. Participants receive weekly injections of survodutide or a placebo for about a year, along with diet and exercise advice. The goal is to see if the drug reduces liver fat and helps with weight loss.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Survodutide (injected weekly)

What this could lead to

If successful, survodutide could offer a new treatment option to reduce liver fat and help with weight loss in people with NASH and obesity.

What could go wrong

This is a Phase 3 trial, but results are not yet published. The drug may not work better than placebo, and side effects are possible. Long-term benefits and safety are still unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

metabolic dysfunction-associated steatohepatitis metabolic dysfunction-associated steatotic liver disease Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NON-ALCOHOLIC STEATOHEPATITIS (NASH) OBESITY

Contacts and locations

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Locations

ARK Clinical Research

Fountain Valley, California, 92708, United States
ARK Clinical Research

Long Beach, California, 92657, United States
Accurate Clinical Research, Inc.

Humble, Texas, 77346, United States
Amel Med LLC

Georgetown, Texas, 78628, United States
Biopharma Informatic, Inc. Research Center

Houston, Texas, 77084, United States
Catalina Research Institute, LLC

Montclair, California, 91763, United States
Clinical Trials of Texas, LLC

San Antonio, Texas, 78229, United States
Covenant Metabolic Specialists, LLC - Fort Myers

Fort Myers, Florida, 33912, United States
Covenant Research and Clinics, LLC

Sarasota, Florida, 34240, United States
DSI Research Northridge LLC

Dayton, Ohio, 45414, United States
Excel Medical Clinical Trials

Boca Raton, Florida, 33434, United States
Fleming Island Center for Clinical Research

Fleming Island, Florida, 32003, United States
GI Select Health Research LLC

Richmond, Virginia, 23236, United States
Gastroenterology and Liver Research LLC

Houston, Texas, 77043, United States
Health Awareness, Inc.

Jupiter, Florida, 33458, United States
Hospital Clínic de Barcelona

Barcelona, 08036, Spain
Hospital Universitari Vall d'Hebron

Barcelona, 08035, Spain
Hospital Universitario La Paz

Madrid, 28046, Spain
Hospital Universitario Ramon Y Cajal

Madrid, 28034, Spain
Indiana University

Indianapolis, Indiana, 46202, United States
Kansas Medical Clinic PA

Topeka, Kansas, 66606-1707, United States
Louisiana Research Center, LLC

Shreveport, Louisiana, 71105, United States
Medical University of South Carolina

Charleston, South Carolina, 29425, United States
Nature Coast Clinical Research-Inverness-48221

Inverness, Florida, 34452, United States
Panax Clinical Research

Miami Lakes, Florida, 33014, United States
Segal Drug Trials

Delray Beach, Florida, 33484, United States
Springfield Clinic, LLP

Springfield, Illinois, 62702, United States
University of Iowa Hospitals and Clinics

Iowa City, Iowa, 52242, United States
Velocity Clinical Research, Austin

Austin, Texas, 78759, United States
Velocity Clinical Research, Santa Ana

Santa Ana, California, 92704, United States
Velocity Clinical Research, Waco

Waco, Texas, 76710, United States
Velocity Clinical Research-Gardena-69773

Gardena, California, 90247, United States
Velocity Clinical Research-Hallandale Beach-67888

Hallandale, Florida, 33009, United States
Velocity Clinical Research-North Hollywood-69852

North Hollywood, California, 91606, United States
Velocity Clinical Research-Panorama City-68861

Panorama City, California, 91402, United States
Verus Clinical Research Corporation

Miami, Florida, 33135, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States