New study tests gentler way to give lung medicine to preterm infants

NCT ID NCT07350018

Recruiting now Disease control Sponsor: Uludag University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two medications (calfactant and poractant alfa) given through a thin tube to help premature babies breathe. The babies are born before 30 weeks and have respiratory distress syndrome. The goal is to see which drug works better at reducing the need for a breathing tube in the first 72 hours of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: surfactants (calfactant and poractant alfa)
What this could lead to: If this trial succeeds, it could show that one surfactant works better than the other when given through a thin tube, potentially improving breathing outcomes for premature babies without needing a breathing tube.
What could go wrong: This is a phase 4 study, so both treatments are already used in practice. The main risk is that the study may not find a clear difference between the two surfactants, or that the less invasive method may not work for all babies.

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Conditions

The condition(s) this trial relates to.

adult acute respiratory distress syndrome Premature Birth respiratory distress syndrome in premature infants

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RESPIRATORY DISTRESS SYNDROME (RDS) RESPIRATORY DISTRESS SYNDROME IN PREMATURE INFANTS SURFACTANT

Contacts and locations

Locations

Bursa City Hospital
RECRUITING

Bursa, Turkey (Türkiye)
Division of Neonatology, Department of Pediatrics, Bursa Uludağ University Faculty of Medicine
RECRUITING

Bursa, Turkey (Türkiye)
Division of Neonatology, Department of Pediatrics, University of Health Sciences Bursa Yuksek İhtisas Training and Research Hospital
RECRUITING

Bursa, Turkey (Türkiye)
Dörtçelik Children's Diseases Hospital
RECRUITING

Bursa, Turkey (Türkiye)
Medicana Bursa Hospital
RECRUITING

Bursa, Turkey (Türkiye)

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