New study tests gentler way to give lung medicine to preterm infants

NCT ID NCT07350018

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two medications (calfactant and poractant alfa) given through a thin tube to help premature babies breathe. The babies are born before 30 weeks and have respiratory distress syndrome. The goal is to see which drug works better at reducing the need for a breathing tube in the first 72 hours of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

surfactants (calfactant and poractant alfa)

What this could lead to

If this trial succeeds, it could show that one surfactant works better than the other when given through a thin tube, potentially improving breathing outcomes for premature babies without needing a breathing tube.

What could go wrong

This is a phase 4 study, so both treatments are already used in practice. The main risk is that the study may not find a clear difference between the two surfactants, or that the less invasive method may not work for all babies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

adult acute respiratory distress syndrome Premature Birth respiratory distress syndrome in premature infants

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Bursa City Hospital

    RECRUITING

    Bursa, Turkey (Türkiye)

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Division of Neonatology, Department of Pediatrics, Bursa Uludağ University Faculty of Medicine

    RECRUITING

    Bursa, Turkey (Türkiye)

    Contact

    Contact

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Division of Neonatology, Department of Pediatrics, University of Health Sciences Bursa Yuksek İhtisas Training and Research Hospital

    RECRUITING

    Bursa, Turkey (Türkiye)

    Contact

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Dörtçelik Children's Diseases Hospital

    RECRUITING

    Bursa, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Medicana Bursa Hospital

    RECRUITING

    Bursa, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact