New dialyzer aims to cut down on dialysis symptoms

NCT ID NCT06032208

Recruiting now Symptom relief Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a new type of dialyzer, called Theranova, can help reduce common symptoms like pain, fatigue, and poor sleep in people with end-stage renal disease who are on dialysis. About 100 participants will use their usual dialyzer for the first 4 weeks and then switch to the Theranova dialyzer for 24 weeks, reporting their symptoms through a simple app. The goal is to see if removing larger toxins from the blood improves how patients feel.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Theranova dialyzer (a device used during hemodialysis to remove larger toxins)
What this could lead to: If it works, this could lead to better symptom management and improved quality of life for people on dialysis.
What could go wrong: This is a small, early-stage extension study with no control group, so results may not be conclusive. The new dialyzer may not significantly improve symptoms compared to standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

END-STAGE RENAL DISEASE

Contacts and locations

Locations

QEII Health Sciences Centre, Nova Scotia Health
RECRUITING

Halifax, Nova Scotia, B3H 1V7, Canada
Seven Oaks Hospital Chronic Disease Innovation Centre Inc. (CDIC)
RECRUITING

Winnipeg, Manitoba, R2V 3M3, Canada
Victoria Hospital, London Health Sciences Centre
RECRUITING

London, Ontario, N6A 5W9, Canada
Westmount Kidney Care Centre
RECRUITING

London, Ontario, N6K 1M6, Canada

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