Can a blood thinner or a device prevent strokes after a brain bleed?

NCT ID NCT03243175

Recruiting now Disease control Sponsor: University Hospital, Lille Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at people with an irregular heartbeat (atrial fibrillation) who have had a brain bleed. Doctors are unsure if blood thinners are safe for them. The trial compares two options: the blood thinner apixaban or a procedure to close a part of the heart (left atrial appendage closure). The goal is to see which approach better prevents future strokes or bleeding events. 300 adults will take part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Apixaban (Eliquis) and left atrial appendage closure device
What this could lead to: If successful, this could show a safe way to prevent strokes in people with atrial fibrillation who have previously had a brain bleed.
What could go wrong: This is a phase 3 trial, but it is still recruiting and results are not yet available. The risk of another brain bleed remains a concern with any blood thinner.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ATRIAL FIBRILLATION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

atrial fibrillation intracerebral hemorrhage

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION INTRACEREBRAL HEMORRHAGE MICROHAEMORRHAGE

Contacts and locations

Locations

CH De Tourcoing
RECRUITING

Tourcoing, France
GHICL
RECRUITING

Lomme, France
Hôpital Roger Salengro, CHU
RECRUITING

Lille, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.