Can a blood thinner or a device prevent strokes after a brain bleed?
NCT ID NCT03243175
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at people with an irregular heartbeat (atrial fibrillation) who have had a brain bleed. Doctors are unsure if blood thinners are safe for them. The trial compares two options: the blood thinner apixaban or a procedure to close a part of the heart (left atrial appendage closure). The goal is to see which approach better prevents future strokes or bleeding events. 300 adults will take part.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Apixaban (Eliquis) and left atrial appendage closure device
What this could lead to
If successful, this could show a safe way to prevent strokes in people with atrial fibrillation who have previously had a brain bleed.
What could go wrong
This is a phase 3 trial, but it is still recruiting and results are not yet available. The risk of another brain bleed remains a concern with any blood thinner.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CH De Tourcoing
RECRUITINGTourcoing, France
Contact
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GHICL
RECRUITINGLomme, France
Contact
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Hôpital Roger Salengro, CHU
RECRUITINGLille, France
Contact