Should you pause your blood pressure pills before surgery? new study investigates

NCT ID NCT06862115

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether stopping certain blood pressure medications (ACE inhibitors or ARBs) before colorectal cancer surgery can reduce the risk of heart injury. Researchers will monitor 156 adults for signs of heart damage after surgery. The goal is to find the safest way to manage these medications around the time of major abdominal surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

renin angiotensin system inhibitors (ACE inhibitors or ARBs)

What this could lead to

If successful, this could show that stopping these blood pressure drugs before surgery is safe and may reduce heart injury risk.

What could go wrong

This is a small, single-center trial. Results may not apply to all patients, and stopping blood pressure medication could cause other risks like high blood pressure during surgery.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal cancer hypertensive disorder injury Postoperative Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cairo university hospitals

    RECRUITING

    Cairo, Egypt

    Contact Phone: •••-•••-•••• Email: •••••@•••••