Exercise as medicine: new trial tests if running slows Parkinson's
NCT ID NCT04284436
First seen Apr 24, 2026 · Last updated Apr 24, 2026 · Updated 1 time
Summary
This study tests whether high-intensity treadmill exercise can slow the worsening of motor symptoms in people with early-stage Parkinson's disease. 370 participants who have not yet started Parkinson's medication will be assigned to either moderate or high-intensity treadmill workouts four times a week for 12 months. Researchers will measure changes in movement symptoms and brain dopamine activity to see if exercise can help control the disease.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Boston University (Charles River Campus)
RECRUITINGBoston, Massachusetts, 02215, United States
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
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Columbia University Medical Center
RECRUITINGNew York, New York, 10032, United States
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Emory University
RECRUITINGAtlanta, Georgia, 30322, United States
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Iowa State University
RECRUITINGAmes, Iowa, 50011, United States
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Kent State University
RECRUITINGKent, Ohio, 44240, United States
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Louisiana State University
RECRUITINGBaton Rouge, Louisiana, 70803, United States
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Morehouse School of Medicine
ACTIVE_NOT_RECRUITINGAtlanta, Georgia, 30310, United States
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Northwestern University
RECRUITINGChicago, Illinois, 60611, United States
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Ohio Health
RECRUITINGColumbus, Ohio, 43214, United States
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Oregon Health & Science University
RECRUITINGPortland, Oregon, 97239, United States
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Rush University Medical Center
RECRUITINGChicago, Illinois, 60612, United States
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UT Health San Antonio
RECRUITINGSan Antonio, Texas, 78229, United States
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University of Alabama at Birmingham
RECRUITINGBirmingham, Alabama, 35294, United States
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University of Alberta
RECRUITINGEdmonton, Canada
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University of California, San Francisco
RECRUITINGSan Francisco, California, 94143, United States
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University of Cincinnati
RECRUITINGCincinnati, Ohio, 45221, United States
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University of Colorado, Denver
RECRUITINGAurora, Colorado, 80204, United States
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University of Florida
RECRUITINGGainesville, Florida, 32611, United States
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University of Michigan
RECRUITINGAnn Arbor, Michigan, 48109, United States
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University of Minnesota
RECRUITINGMinneapolis, Minnesota, 55455, United States
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University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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University of Pittsburgh
RECRUITINGPittsburgh, Pennsylvania, 15219, United States
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University of Utah
RECRUITINGSalt Lake City, Utah, 84112, United States
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Washington University St. Louis
RECRUITINGSt Louis, Missouri, 63130, United States
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Conditions
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